RLS-0071, A Novel Dual-targeting Anti-inflammatory Agent, Demonstrates Proof of...
RATIONALE: Neutrophils play an important role in several lung diseases such as acute lung injury, adult respiratory distress syndrome (ARDS),...
Read MoreThe EPICC Family of Anti-Inflammatory Peptides: Next Generation Peptides,...
Abstract The EPICC peptides are a family of peptides that have been developed from the sequence of the capsid protein...
Read MoreClassical complement pathway inhibition reduces brain damage in a...
Abstract Perinatal hypoxic ischemic encephalopathy (HIE) remains a major contributor of infant death and long-term disability worldwide. The role played...
Read MoreIncompatible Erythrocyte Transfusion With Lipopolysaccharide Induces Acute Lung Injury...
Acute transfusion reactions can manifest in many forms including acute hemolytic transfusion reaction, allergic reaction and transfusion-related acute lung injury....
Read MoreInhibition of Complement Activation, Myeloperoxidase, NET Formation And Oxidant...
A product of rational molecular design, PA-dPEG24 is the lead derivative of the PIC1 family of peptides with multiple functional...
Read MoreCeftriaxone-Induced Immune Hemolytic Anemia: In Vitro Reversal With Peptide...
We report a case of ceftriaxone-induced immune hemolytic anemia in a 10-year-old with chronic active Epstein-Barr virus disease and hemophagocytic...
Read MoreInhibition of Immune Complex Complement Activation And Neutrophil Extracellular...
Abstract: Two major aspects of systemic lupus erythematosus (SLE) pathogenesis that have yet to be targeted therapeutically are immune complex-initiated...
Read MorePeptide Inhibitor Of Complement C1 (PIC1) Demonstrates Antioxidant Activity...
Reactive oxygen species (ROS) are natural byproducts of oxidative respiration that are toxic to organs and tissues. To mitigate ROS...
Read MorePeptide Inhibitor Of Complement C1 (PIC1) Inhibits Growth Of...
Peptide Inhibitor of Complement C1 (PIC1) is a family of 15 amino acid peptides that inhibit complement activation via the...
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