Our science

Abstracts

ReAlta Life Sciences Has A Strong Series Of Publications In Peer-Reviewed Scientific Journals

Dec 20, 2016

Discriminating The Hemolytic Risk Of Blood Type A Plasmas...

Diabetic non-healing wounds are a major clinical problem. The mechanisms leading to poor wound healing in diabetes are multifactorial but...

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Jun 10, 2016

Peptide Inhibitor Of Complement C1 Modulates Acute Intravascular Hemolysis...

Acute hemolytic transfusion reactions have a broad clinical presentation from mild and transitory signs and symptoms to shock, disseminated intravascular...

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Dec 07, 2015

Complement Effectors Of Inflammation In Cystic Fibrosis Lung Fluid...

In cystic fibrosis (CF), lung damage is mediated by a cycle of obstruction, infection, and inflammation. Here we explored complement...

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Jun 21, 2015

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement...

The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases....

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Aug 22, 2014

Peptide Inhibitor Of Complement C1, A Novel Suppressor Of...

The classical pathway of complement plays multiple physiological roles including modulating immunological effectors initiated by adaptive immune responses and an...

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Jan 24, 2014

Clinical Hypothermia Temperatures Increase Complement Activation And Cell Destruction...

Therapeutic hypothermia is a treatment modality that is increasingly used to improve clinical neurological outcomes for ischemia-reperfusion injury-mediated diseases. Antibody-initiated...

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Aug 18, 2012

A Novel Peptide Inhibitor Of Classical And Lectin Complement...

Previous experiments from our laboratories have identified peptides derived from the human astrovirus coat protein (CP) that bind C1q and...

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Aug 20, 2010

Potent Inhibition Of The Classical Pathway Of Complement By...

Previous work from our laboratories has demonstrated that purified, recombinant human astrovirus coat protein (HAstV CP) binds C1q and mannose-binding...

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Nov 06, 2009

Human astrovirus coat protein binds C1q and MBL and...

Human astroviruses (HAstVs) constitute a family of non-enveloped, RNA viruses which cause infantile gastroenteritis. We have previously demonstrated that purified...

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