A complement-mediated rat xenotransfusion model of platelet refractoriness
Background: Platelet refractoriness remains a challenging clinical dilemma although significant advancements have been made in identifying human leukocyte antigen (HLA)...
Read MoreIncompatible Erythrocyte Transfusion With Lipopolysaccharide Induces Acute Lung Injury...
Acute transfusion reactions can manifest in many forms including acute hemolytic transfusion reaction, allergic reaction and transfusion-related acute lung injury....
Read MoreClassical complement activation on human erythrocytes in subjects with...
Introduction: Autoimmune hemolytic anemia (AIHA) is a serious manifestation of systemic lupus erythematosus (SLE) associated with significant morbidity and mortality....
Read MoreInhibition of Complement Activation, Myeloperoxidase, NET Formation And Oxidant...
A product of rational molecular design, PA-dPEG24 is the lead derivative of the PIC1 family of peptides with multiple functional...
Read MoreCeftriaxone-Induced Immune Hemolytic Anemia: In Vitro Reversal With Peptide...
We report a case of ceftriaxone-induced immune hemolytic anemia in a 10-year-old with chronic active Epstein-Barr virus disease and hemophagocytic...
Read MoreInhibition of Immune Complex Complement Activation And Neutrophil Extracellular...
Abstract: Two major aspects of systemic lupus erythematosus (SLE) pathogenesis that have yet to be targeted therapeutically are immune complex-initiated...
Read MorePeptide Inhibitor Of Complement C1 (PIC1) Demonstrates Antioxidant Activity...
Reactive oxygen species (ROS) are natural byproducts of oxidative respiration that are toxic to organs and tissues. To mitigate ROS...
Read MorePeptide Inhibitor Of Complement C1 (PIC1) Inhibits Growth Of...
Peptide Inhibitor of Complement C1 (PIC1) is a family of 15 amino acid peptides that inhibit complement activation via the...
Read MorePeptide Inhibitor Of Complement C1 Inhibits The Peroxidase Activity...
Hemoglobin is the natural carrier of oxygen in red blood cells (RBCs). While intracellular hemoglobin provides life-sustaining oxygen transport, extracellular...
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